Are you concerned about Imipramine safety?

As with any medication, you need to be careful of taking the correct dosage, at the correct time, and avoiding other medications that will cause a reaction if taken at the same time.

However, you also need to be careful of Imipramine side effects.

Today we will cover the above topics to give you some practical ways to take your Imipramine dosage in the safest way possible.

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How is imipramine taken?

Imipramine (also known as Janimine, Tofranil, Imipramine HCL or Tofranil PM) comes in two forms: tablets and capsules taken orally. When used for depression, imipramine is taken once a day or as necessary (can be more than once a day) and with or without food.

For nocturia in children, the medication is given an hour before bedtime. If a child wets the bed earlier during the night, then it is also advisable to give two doses – one in the afternoon and the other before bedtime.

Other instructions in taking the drug include: taking imipramine at the same time daily, following doctor’s orders and prescription, reading the label carefully, and clarifying with the physician or pharmacist any questions or issues about the drug.

Sometimes, your physician starts on a low-dose imipramine but increases it gradually as needed.

Do not be alarmed if you do not feel instant effects of the drug since it takes around 1-3 weeks before full desired effects of imipramine are achieved – this means you should not stop taking the drug even if you feel better. Aside from this, your physician might also taper down the dosage.

Other indications of the drug

Imipramine can also be indicated for anxiety disorders (such as panic attacks) and eating disorders (such as anorexia nervosa and bulimia nervosa). Speak to your physician about potential risks of taking imipramine.

There are other unofficial indications of imipramine – it as advised that you speak with your physician and pharmacist for more details.

What precautionary measures should be followed?

Prior to taking in imipramine

* Determine any allergies to the drug and inform your healthcare team.

* If you are on a monoamine oxidase inhibitor (MAOI) therapy like isocarboxazid (Marplan), selegiline (Eldepryl), phenelzine (Nardil), and tranylcypromine (Parnate), and if you have discontinued taking MAOI within 2 weeks. Your physician will most probably contraindicate imipramine to you. If you are taking in imipramine, allow a minimum of 2 weeks before starting on MAOI.

* Discuss with your physician or pharmacist what you intend to eat or take in concurrent with imipramine like supplements, vitamins, herbal preparations, and so on.

* Take importance and mention the following drugs: anticoagulants, antihistamines, dopamine preparations, other antidepressants and psych drugs, cardiovascular drugs (antihypertensives such as Beta Blockers, Calcium Channel blockers, ACE inhibitors), anti-asthma drugs, anti-seizures, sedatives, barbiturates, thyroid hormones, and tranquilizers.

*If you are experiencing side effects your doctor may adjust the dosage. Make sure to monitor for any adverse effects.

* If you have taken in fluoxetine within 35 days, your doctor may contraindicate imipramine. Inform your doctor if you experienced a recent heart attack as you may also be advised not to take imipramine.

* Nicotine decreases the effectiveness of imipramine so inform your physician if you are using tobacco products.

* Imipramine causes photosensitivity (increases sensitivity to sunlight). Make sure you ask your physician about sun exposure, sunscreen products, and other protective barriers against sunlight.

* Inform your physician if you have the following diseases: glaucoma (increase in eye pressure), benign prostatic hyperplasia (non-malignant enlargement of the prostate), dysuria (difficulty in voiding), active seizures or epilepsy, thyroid problems, hepatic (liver) and renal (kidney) problems.

* Inform your healthcare team if you are undergoing any kind of surgery (dental, abdominal, cardiovascular, etc.)

* Inform your physician if you are planning on becoming pregnant, already pregnant, or currently breast-feeding.

* Imipramine causes sedation (drowsiness) therefore you are not allowed to operate machineries, drive, or perform other activities that need alertness.

* NEVER consume alcohol with imipramine because it increases sedation.

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